Examining the convergence of dominant themes related to social entrepreneurship, NGOs and globalization-A systematic literature review.

Social entrepreneurship (SE) is an all-encompassing concept in comparison to a typical non-government organization (NGO). It is a topic that has captured the interest of academics investigating nonprofit, charitable, and nongovernmental organizations. Despite the interest, few studies have examined the overlap and convergence of entrepreneurship and non-governmental organizations (NGOs), in congruence with the new phase of globalization. The study gathered and evaluated 73 peer-reviewed papers using a systematic literature review methodology, mainly from Web of Science but also from Scopus, JSTOR, and Science Direct, and supplemented by a search of existing databases and bibliographies. Based on the findings, 71 percent of studies suggest that organizations must reconsider the concept of social work, which has evolved rapidly, aided by globalization. The concept has changed from the NGO model to a more sustainable one, such as that proposed by SE. However, it is difficult to draw broad generalizations regarding the convergence of context-dependent complex variables such as SE, NGOs, and globalization. The results of the study will significantly contribute to a better understanding of the convergence of SE and NGOs, as well as the recognition that many aspects of NGOs, SE, and post-COVID globalization remain unexamined.

Post-pandemic tourism strategies: A case of Himachal Pradesh.

Tourism has always been a vulnerable industry. Minimal disturbances can halt or even destroy tourism and its associated economy. There is no dearth of research on vulnerability and resilience of the tourism industry for various tourism destinations,, and on post-disaster studies, but mainly these were limited to a city or tourist destination and focused on the destination image recovery. The primary purpose of this study is to identify different tourism stages and the local community's issues and desires associated with each stage and to propose strategies that can be used during and after the COVID-19 pandemic. The district-wise monthly domestic and foreign tourist arrival data from 2008 to 2018 for Himachal Pradesh (HP) were observed. The observations reveal that HP experiences overtourism, balanced tourism, and undertourism. Two hundred seven telephonic interviews were conducted with different stakeholders such as tourism department officers, urban planners, hotel owners and managers, environmentalists, and state residents. Research themes were identified based on the interview responses, and these themes were further validated using a review of newspaper reports and court and local administration order. This study identified nine broad problems and patterns associated with tourism and proposes 17 sustainable tourism strategies that the post-COVID-19 crisis can follow. The proposed strategies give special attention to confidence-building of tourist and residents, image building of the location, and increasing tourism number sustainably and tourism earning of the state. This study investigates problems and suggests sustainable strategies for a state in India for the first time and may be used for policy decision and regional sustainable tourism development plan.

Mental health concerns during the COVID-19 pandemic as revealed by helpline calls.

Mental health is an important component of public health, especially in times of crisis. However, monitoring public mental health is difficult because data are often patchy and low-frequency1-3. Here we complement established approaches by using data from helplines, which offer a real-time measure of 'revealed' distress and mental health concerns across a range of topics4-9. We collected data on 8 million calls from 19 countries, focusing on the COVID-19 crisis. Call volumes peaked six weeks after the initial outbreak, at 35% above pre-pandemic levels. The increase was driven mainly by fear (including fear of infection), loneliness and, later in the pandemic, concerns about physical health. Relationship issues, economic problems, violence and suicidal ideation, however, were less prevalent than before the pandemic. This pattern was apparent both during the first wave and during subsequent COVID-19 waves. Issues linked directly to the pandemic therefore seem to have replaced rather than exacerbated underlying anxieties. Conditional on infection rates, suicide-related calls increased when containment policies became more stringent and decreased when income support was extended. This implies that financial relief can allay the distress triggered by lockdown measures and illustrates the insights that can be gleaned from the statistical analysis of helpline data.

A Basis to Be Here: Stories from International Graduate Students in the United States.

Recent guidance from the US Immigration and Customs Enforcement drastically altered the lives of international students in America, especially those who are matriculating. This commentary describes how international students still face uncertainty concerning their visa statuses and their place in American society.

USA stockpiling of remdesivir: How should the world respond?

The race to find an effective treatment for coronavirus disease 2019 (COVID-19) is still on, with only two treatment options currently authorized for emergency use and/or recommended for patients hospitalized with severe respiratory symptoms: low-dose dexamethasone and remdesivir. The USA decision to stockpile the latter has resulted in widespread condemnation and in similar action being taken by some other countries. In this commentary we discuss whether stockpiling remdesivir is justified in light of the currently available evidence.

Do Environmental Regulations Facilitate a Low-Carbon Transformation in China's Resource-Based Cities?

Resource-based cities (RBCs) are not only important for ensuring national resource and energy security, but they also face serious ecological and environmental problems. To achieve China's carbon peaking and neutrality goals in the coming years, RBCs' achievement of a low-carbon transformation has become increasingly significant. The core of this study is an investigation as to whether governance, including environmental regulations, can facilitate the low-carbon transformation of RBCs. Based on RBC data from 2003 to 2019, we establish a dynamic panel model to research the influence and mechanism of environmental regulations on low-carbon transformation. We found that China's environmental regulations facilitate a low-carbon transformation in RBCs. Mechanism analysis identified that the environmental regulations facilitate the low-carbon transformation in RBCs by strengthening foreign direct investment, enhancing green technology innovation and promoting industrial structure upgrading. Heterogeneity analysis found that the environmental regulations play a greater role in facilitating the low-carbon transformation of RBCs in regions with more developed economies and less dependence on resources. Our research provides theoretical and policy implications for environmental regulations for the low-carbon transformation of RBCs in China, applicable to other resource-based areas.

FDI and Wellbeing: A Key Node Analysis for Psychological Health in Response to COVID-19 Using Artificial Intelligence.

Developing countries are primary destinations for FDI from emerging economies following the World Investment Report 2022, including destinations in OECD countries. Based on three theoretical lenses and case analyses, we argue that Chinese outward FDI has impacts on wellbeing in destination countries, and that this is an important issue for psychological health in response to COVID-19. Based on the super-efficiency DEA approach, our study investigated the impact of Chinese outward FDI on wellbeing in OECD countries. We also applied a Tabu search to identify country groups based on the relationship between Chinese outward FDI and wellbeing and we developed a key node analysis of the country groups using an immune algorithm. This research has implications for public administrators in global governance and could help shape FDI policies to improve psychological health of the destination countries in response to COVID-19.

Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults.

BACKGROUND: Respiratory syncytial virus (RSV) is an important cause of acute respiratory infection, lower respiratory tract disease, clinical complications, and death in older adults. There is currently no licensed vaccine against RSV infection. METHODS: In an ongoing, international, placebo-controlled, phase 3 trial, we randomly assigned, in a 1:1 ratio, adults 60 years of age or older to receive a single dose of an AS01E-adjuvanted RSV prefusion F protein-based candidate vaccine (RSVPreF3 OA) or placebo before the RSV season. The primary objective was to show vaccine efficacy of one dose of the RSVPreF3 OA vaccine against RSV-related lower respiratory tract disease, confirmed by reverse-transcriptase polymerase chain reaction (RT-PCR), during one RSV season. The criterion for meeting the primary objective was a lower limit of the confidence interval around the efficacy estimate of more than 20%. Efficacy against severe RSV-related lower respiratory tract disease and RSV-related acute respiratory infection was assessed, and analyses according to RSV subtype (A and B) were performed. Safety was evaluated. RESULTS: A total of 24,966 participants received one dose of the RSVPreF3 OA vaccine (12,467 participants) or placebo (12,499). Over a median follow-up of 6.7 months, vaccine efficacy against RT-PCR-confirmed RSV-related lower respiratory tract disease was 82.6% (96.95% confidence interval [CI], 57.9 to 94.1), with 7 cases (1.0 per 1000 participant-years) in the vaccine group and 40 cases (5.8 per 1000 participant-years) in the placebo group. Vaccine efficacy was 94.1% (95% CI, 62.4 to 99.9) against severe RSV-related lower respiratory tract disease (assessed on the basis of clinical signs or by the investigator) and 71.7% (95% CI, 56.2 to 82.3) against RSV-related acute respiratory infection. Vaccine efficacy was similar against the RSV A and B subtypes (for RSV-related lower respiratory tract disease: 84.6% and 80.9%, respectively; for RSV-related acute respiratory infection: 71.9% and 70.6%, respectively). High vaccine efficacy was observed in various age groups and in participants with coexisting conditions. The RSVPreF3 OA vaccine was more reactogenic than placebo, but most adverse events for which reports were solicited were transient, with mild-to-moderate severity. The incidences of serious adverse events and potential immune-mediated diseases were similar in the two groups. CONCLUSIONS: A single dose of the RSVPreF3 OA vaccine had an acceptable safety profile and prevented RSV-related acute respiratory infection and lower respiratory tract disease and severe RSV-related lower respiratory tract disease in adults 60 years of age or older, regardless of RSV subtype and the presence of underlying coexisting conditions. (Funded by GlaxoSmithKline Biologicals; AReSVi-006 ClinicalTrials.gov number, NCT04886596.).

Health system adaptions to improve care for people living with non-communicable diseases during COVID-19 in low-middle income countries: A scoping review.

Background: During the COVID-19 pandemic, access to health care for people living with non-communicable diseases (NCDs) has been significantly disrupted. Calls have been made to adapt health systems and innovate service delivery models to improve access to care. We identified and summarized the health systems adaptions and interventions implemented to improve NCD care and their potential impact on low- and middle-income countries (LMICs). Methods: We comprehensively searched Medline/PubMed, Embase, CINAHL, Global Health, PsycINFO, Global Literature on coronavirus disease, and Web of Science for relevant literature published between January 2020 and December 2021. While we targeted articles written in English, we also included papers published in French with abstracts written in English. Results: After screening 1313 records, we included 14 papers from six countries. We identified four unique health systems adaptations/interventions for restoring, maintaining, and ensuring continuity of care for people living with NCDs: telemedicine or teleconsultation strategies, NCD medicine drop-off points, decentralization of hypertension follow-up services and provision of free medication to peripheral health centers, and diabetic retinopathy screening with a handheld smartphone-based retinal camera. We found that the adaptations/interventions enhanced continuity of NCD care during the pandemic and helped bring health care closer to patients using technology and easing access to medicines and routine visits. Telephonic aftercare services appear to have saved a significant amount of patients' time and funds. Hypertensive patients recorded better blood pressure controls over the follow-up period. Conclusions: Although the identified measures and interventions for adapting health systems resulted in potential improvements in access to NCD care and better clinical outcomes, further exploration is needed to establish the feasibility of these adaptations/interventions in different settings given the importance of context in their successful implementation. Insights from such implementation studies are critical for ongoing health systems strengthening efforts to mitigate the impact of COVID-19 and future global health security threats for people living with NCDs.

The Nursing Shortage: Foreign-Educated Workers Are Only a Stopgap.

Worldwide shortages require action to shore up the U.S. workforce.

Pattern changes of ecological product trade in countries along the Belt and Road.

The Belt and Road Initiative (BRI) was designed to promote economic and trade cooperation between countries along the Belt and Road (B&R), specifically by building an international trade network. Ecological resources are the basis for human survival. Countries along the B&R transform ecological resources into ecological products by production activities. These products can then be used for trade, thereby driving the countries' economic development. This study uses net primary productivity (NPP) as a unified measure of ecological products, and explores the pattern changes of ecological product trade in countries along the B&R, from 2013 to 2019 (from the BRI proposal to the outbreak of COVID-19). The purpose of the study is to reveal the impact of the BRI on the trade of ecological products. The results show that (1) the trade scale of ecological products in the B&R region has changed significantly. The total volume of traded ecological products increased from 2071.74 to 2631.00 TgC. This represented an increase of about 26.99%, or 7.41% higher than the global average. (2) The spatial distribution pattern of ecological product trade did not change significantly in countries along the B&R. However, the gravity centers of the total and net trade volume of ecological products moved 120.74 km to the northeast and 392.98 km to the southeast, respectively. (3) The trade structure of ecological products in the B&R region, six sub-regions, and most countries remained relatively stable. Only the proportion of the livestock products trade in Mongolia and the proportion of the forest products trade in Bhutan have increased significantly. This finding suggests that the strength and breadth of the construction of unimpeded trade in countries along the B&R still need to further strengthened, in order to accelerate the realization of the vision of the Green Silk Road.

COVoc and COVTriage: novel resources to support literature triage.

MOTIVATION: Since early 2020, the coronavirus disease 2019 (COVID-19) pandemic has confronted the biomedical community with an unprecedented challenge. The rapid spread of COVID-19 and ease of transmission seen worldwide is due to increased population flow and international trade. Front-line medical care, treatment research and vaccine development also require rapid and informative interpretation of the literature and COVID-19 data produced around the world, with 177 500 papers published between January 2020 and November 2021, i.e. almost 8500 papers per month. To extract knowledge and enable interoperability across resources, we developed the COVID-19 Vocabulary (COVoc), an application ontology related to the research on this pandemic. The main objective of COVoc development was to enable seamless navigation from biomedical literature to core databases and tools of ELIXIR, a European-wide intergovernmental organization for life sciences. RESULTS: This collaborative work provided data integration into SIB Literature services, an application ontology (COVoc) and a triage service named COVTriage and based on annotation processing to search for COVID-related information across pre-defined aspects with daily updates. Thanks to its interoperability potential, COVoc lends itself to wider applications, hopefully through further connections with other novel COVID-19 ontologies as has been established with Coronavirus Infectious Disease Ontology. AVAILABILITY AND IMPLEMENTATION: The data at https://github.com/EBISPOT/covoc and the service at https://candy.hesge.ch/COVTriage.